Rivastigmine in Wernicke-Korsakoff's syndrome: Five patients with rivastigmine showed no more improvement than five patients without rivastigmine

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Case Report Rivastigmine in Wernicke-korsakoff’s Syndrome: Five Patients with Rivastigmine Showed No More Improvement than Five Patients without Rivastigmine

Aims: To evaluate whether rivastigmine, an achetylcholinesterase inhibitor (AChEl), may be effective in restoring memory in Wernicke-Korsakoff’s syndrome (WKS). Methods: Five patients treated with rivastigmine for a period of 6 months were compared with five matched control patients, who received 6 months’ conventional treatment, but without rivastigmine. Memory tests were administered at basel...

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Rivastigmine in Wernicke-Korsakoff's syndrome: five patients with rivastigmine showed no more improvement than five patients without rivastigmine.

AIMS To evaluate whether rivastigmine, an achetylcholinesterase inhibitor (AChEl), may be effective in restoring memory in Wernicke-Korsakoff's syndrome (WKS). METHODS Five patients treated with rivastigmine for a period of 6 months were compared with five matched control patients, who received 6 months' conventional treatment, but without rivastigmine. Memory tests were administered at basel...

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Rivastigmine (Exelon) for dementia in patients with Parkinson's disease.

OBJECTIVES To study the efficacy of cholinesterase inhibitors in the treatment of dementia in patients with Parkinson's disease (PD). METHODS We treated twenty-eight demented patients with PD openly for 26 weeks with rivastigmine (mean daily dose 7.2 +/- 3.3 mg/day). Baseline scores were compared with those at weeks 12, 26 and after 8 weeks of washout. RESULTS Twenty patients completed 26 w...

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Rivastigmine in Chinese patients with subcortical vascular dementia

BACKGROUND We explored the efficacy and tolerability of rivastigmine among Chinese patients with subcortical vascular dementia. METHODS Forty subjects were randomized to either placebo (n = 20) or rivastigmine (n = 20) in a double-blind 26-week trial. Outcome measures were cognition (mini-mental state examination, frontal assessment battery), neuropsychiatric inventory (NPI), instrumental act...

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Economic evaluation of rivastigmine in patients with Parkinson's disease dementia.

BACKGROUND The positive results of a randomised clinical trial of rivastigmine in patients with dementia associated with Parkinson's disease have been published recently. Patient-level healthcare utilisation data were also collected, and this report is the economic evaluation based on these data. OBJECTIVE To determine the cost effectiveness of rivastigmine 3-12 mg/day in patients in whom mil...

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ژورنال

عنوان ژورنال: Alcohol and Alcoholism

سال: 2007

ISSN: 0735-0414,1464-3502

DOI: 10.1093/alcalc/agm158